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Coagulation

Test Code Procedure
300908 Abnormal APTT/Prothrombin Time Reflexive Evaluation (APTT, Prothrombin Time/INR, Thrombin Time) Note: Additional assays as necessary will be performed at an additional charge to determine the cause of the abnormality.
300716 Activated Protein C Resistance (APCR) with Factor V Deficient Plasma
300737 Activated Protein C Resistance (APCR) without Factor V Deficient Plasma
  ADAMTS-13 - see 300326- von Willebrand Protease Activity and Protease Inhibitor
300039 Alpha-2-Antiplasmin Assay
300233 Anti-Annexin V IgG, IgM *RUO*
300034 Anticardiolipin Antibodies, IgA, IgG, IgM
300165 Anticardiolipin Antibodies, IgG, IgM
300164 Anticardiolipin Antibody, IgA
300161 Anticardiolipin Antibody, IgG
300162 Anticardiolipin Antibody, IgM
300153 Antiphosphatidylserine (APTS) IgG, IgM
300918 Antiphospholipid Syndrome Comprehensive Evaluation (APTT, Immediate Mixing Studies, Anticardiolipin Antibodies (IgG, IgM, IgA), Antiphosphatidylserine Antibodies (IgG, IgM), Beta-2-Glycoprotein I Antibodies (IgG, IgM, IgA), Antiprothrombin Antibodies (IgG, IgM), DRVVT, Hexagonal Phospholipid Neutralization, Platelet Neutralization Procedure)
300230 Antiprothrombin Antibodies IgG, IgM
300030 Antithrombin Activity
300033 Antithrombin Antigen
  APCR - see 300716 - Activated Protein C Resistance
300040 APTT
300806 APTT Mixing Studies (APTT, APTT 1:1 NP Mix, APTT 1:1 NP Control Mix, APTT 1:1 Saline Mix, APTT 1:1 NP 60 min. Incubation, APTT 1:1 NP Control 60 min. Incubation)
  ArixtraŽ - see 300864- Heparin Anti-Xa Fondaparinux
300353 AspirinWorks
300166 Beta-2 Glycoprotein I, IgA, IgG, IgM
300909 Bleeding Diathesis with a Normal APTT/PT Evaluation (Factor VIII Activity, von Willebrand Factor Activity, von Willebrand Factor Antigen, Factor IX Activity, Factor XI Activity, Plasminogen Activator Inhibitor - 1 Activity, Alpha 2 Antiplasmin Activity, Factor XIII Activity *RUO*, Euglobulin Lysis Time)
300160 C4b Binding Protein *RUO*
  CBA - see 300314 - Collagen Binding Assay
300314 Collagen Binding Assay (VWF collagen binding activity *RUO*, VWF antigen, Collagen binding ratio)
300924 Contact Factor Evaluation (Factor XI Activity, Factor XII Activity, High Molecular Weight Kininogen (Fitzgerald Factor) Assay, Prekallikrein (Fletcher Factor ) Assay)
300312 C-Reactive Protein, High Sensitivity (hs CRP)
300203 Cryofibrinogen
300749 CYP2C9 Polymorphism Warfarin hypersensitivity Genotyping
300415 D-Dimer Quantitative (Automated)
300057 Dilute Russell's Viper Venom Test (DRVVT)
  Drug Induced Platelet Antibody - see 300521 - Platelet Antibody, Drug Induced
300814 Ecarin Clotting Time *RUO*
300403 Euglobulin Lysis Time
300920 Extrinsic Pathway Evaluation Profile (Factor II Activity, Factor V Activity, Factor VII Activity, Factor X Activity)
300700 Factor Inhibitor Screen (APTT, PT, Thrombin Time, APTT 1:1 NP, APTT 1:1 Saline, APTT 1:1 NP 60 min. incubation, APTT 1:1 NP Control 60 min. incubation, Inhibitor Screen interpretation)
300100 Factor II Activity (Prothrombin Activity)
120736 Factor II Gene Mutation (Prothrombin G20210A)
300724 Factor II Inhibitor (Bethesda) (APTT, PT, PT 1:1 NP, PT 1:1 NP 60 min. incubation, PT 1:1 NP control 60 min. incubation, Factor II Activity, Factor II Bethesda Titer)
300101 Factor V Activity
300706 Factor V Inhibitor (Bethesda) (APTT, PT, PT 1:1 NP, Factor V Activity, Factor V Bethesda Titer)
120719 Factor V Leiden Mutation
300102 Factor VII Activity
300112 Factor VII Antigen *RUO*
300721 Factor VII Inhibitor (Bethesda) (APTT, PT, PT 1:1 NP, Factor VII Activity, Factor VII Bethesda Titer)
300103 Factor VIII Activity
300690 Factor VIII Antibody, Immunologic
300208 Factor VIII Antigen
300188 Factor VIII Bethesda Titer (Factor VIII Activity and Factor VIII Bethesda titer only)
300214 Factor VIII Chromogenic Activity
300213 Factor VIII Chromogenic Activity - RefactoTM
300701 Factor VIII Inhibitor Human (Bethesda) (APTT, APTT 1:1 NP, APTT 1:1 saline, APTT 1:1 NP 60 min. incubation, APTT 1:1 NP control 60 min. incubation, Factor VIII Activity, Factor VIII Bethesda Titer)
  Factor VIII Related Antigen - see 300113 - von Willebrand Factor Antigen
300104 Factor IX Activity
300205 Factor IX Antigen
300189 Factor IX Bethesda Titer (Factor IX Activity and Factor IX Bethesda titer only)
300704 Factor IX Inhibitor (Bethesda) (APTT, APTT 1:1 NP, APTT 1:1 saline, APTT 1:1 NP 60 min. incubation, APTT 1:1 NP control 60 min. incubation, Factor IX Activity, Factor IX Bethesda Titer)
300105 Factor X Activity
300206 Factor X Antigen *RUO*
300211 Factor X Chromogenic (for Oral Anticoagulant Therapy)
300215 Factor X Chromogenic (not on Oral Anticoagulant)
300725 Factor X Inhibitor (Bethesda) (APTT, PT, PT 1:1 NP, PT 1:1 NP 60 minute incubation, PT 1:1 NP control 60 minute incubation, Factor X Activity, Factor X Bethesda Titer)
300106 Factor XI Activity
300707 Factor XI Inhibitor (Bethesda) (APTT, APTT 1:1 NP, APTT 1:1 saline, APTT 1:1 NP 60 min. incubation, APTT 1:1 NP control 60 min. incubation, Factor XI Activity, Factor XI Bethesda Titer)
300107 Factor XII Activity
300708 Factor XII Inhibitor (Bethesda) (APTT, APTT 1:1 NP, APTT 1:1 saline, APTT 1:1 NP 60 min. incubation, APTT 1:1 NP control 60 min. incubation, Factor XII Activity, Factor XII Bethesda Titer)
300108 Factor XIII Activity *RUO*
300309 Factor XIII Inhibitor Profile *RUO* (Factor XIII Activity, Factor XIII Inhibitor Screen, Factor XIII Titer)
300308 Factor XIII Inhibitor Screen *RUO*
  FDP - see 300201 - Fibrin Degradation Products (FDP)
300201 Fibrin Degradation Products (FDP)
300202 Fibrin Monomer
300200 Fibrinogen Activity
300199 Fibrinogen Antigen
300925 Fibrinogen Evaluation (Fibrinogen Activity, Fibrinogen Antigen, Reptilase Time, Thrombin Time, Thrombin Time Mixing Studies)
300913 Fibrinolysis Evaluation (Alpha-2-Antiplasmin, D-Dimer Quantitative, Euglobulin Lysis Time, Fibrin Degradation Products, Plasminogen Activator Inhibitor-1 Activity, Plasminogen Activity, Tissue Plasminogen Activator Antigen)
  Fitzgerald Factor (HMW Kininogen) - see - 300123 - High Molecular Weight Kininogen
  Fletcher Factor (Prekallikrein) Assay - see - 300121 Preallikrein Assay
  FSP (Fibrin Split Products) - see 300201 - Fibrin Degradation Products (FDP)
300917 Heart Disease and Stroke Risk Profile (Fibrinogen Activity, High Sensitivity CRP, Homocysteine, Lipoprotein (a), von Willebrand Factor Antigen)
300927 Heart Disease and Stroke Risk Profile- Follow-up (APTT, 11-Dehydro Thromboxane B2/Creatinine Ratio *RUO*, Factor VII Activity, Plasminogen Activator Inhibitor-1 Activity)
300600 Heparin Anti-Xa (Unfractionated)
300864 Heparin Anti-Xa Fondaparinux (ArixtraŽ)
300602 Heparin Anti-Xa LMWH (Dalteparin, Enoxaparin)
300133 Heparin Cofactor II *RUO*
  Heparin Induced Antibody Assay, Functional see 300082 - Serotonin Release Assasy (C4)
300935 Heparin Induced Antibody Evaluation (Heparin Induced Platelet Antibody, HITA normalized OD ratio, Serotonin Release Assay (specify heparin type))
300522 Heparin-Induced Platelet Antibody, Immunologic (Heparin Induced Antibody, HITA normalized OD ratio)
300528 Heparin-Induced Antibody Titer
300937 Heparin Induced Antibody Reflexive Evaluation (Heparin Induced Platelet Antibody, HITA normalized OD ratio, Reflex to Serotonin Release Assay if antibody by ELISA is positive or borderline)
300139 Heparin Solution Quantitative Assay
300144 Hexagonal Phospholipid Neutralization
300123 High Molecular Weight Kininogen (Fitzgerald Factor Assay)
  See 300312 - C-Reactive Protein, High Sensitivity
300727 Homocysteine
300531 HPA-1a (PLA-1Platelet Antigen) Genotyping (PLA2 Polymorphism Detection)
300734 HR2 Haplotype (Factor V HR2), A4070G Polymorphism
300229 Immunoglobulin IgA, Quantitative
300227 Immunoglobulin IgG, Quantitative
300228 Immunoglobulin IgM, Quantitative
603005 Immunoglobulin Profile (IgA, IgG, & IgM)
300921 Intrinsic Pathway Evaluation Profile (Factor VIII Activity, Factor IX Activity, Factor XI Activity, Factor XII Activity)
300056 Kaolin Clotting Time (KCT)
300715 Lipoprotein (a)
300916 Lupus Anticoagulant and Anticardiolipin Antibody Confirmatory Profile (APTT, APTT Immediate Mixing Studies, Prothrombin Time/INR, Anticardiolipin Antibody (IgG, IgM), Dilute Russell's Viper Venom Test, Thrombin Time, Hexagonal Phospholipid Neutralization, Platelet Neutralization Procedure)
300906 Lupus Anticoagulant and Anticardiolipin Antibody Evaluation (APTT, APTT Immediate Mixing Studies, Prothrombin Time/INR, Anticardiolipin Antibody (IgG, IgM), Dilute Russell's Viper Venom Test, Thrombin Time, hexagonal phospholipid neutralization)
300939 Markers of Coagulation Activation (Thrombin-Antithrombin Complex (TAT), Prothrombin Fragment 1.2, D-Dimer quant)
300934 Menorrhagia Evaluation (APTT, Prothrombin Time/INR, Factor VIII Activity, von Willebrand Factor Activity, von Willebrand Factor Antigen, Factor XI Activity)
300744 Methylmalonic Acid, Serum***
300711 MMP-9 *RUO* (Matrix Metalloproteinase-9)
120740 MTHFR A1298C Mutation (Methylene Tetrahydrofolate Reductase)
120733 MTHFR C677T Mutation (Methylene Tetrahydrofolate Reductase)
129300 MTHFR Reflex (Heterozygous reflexes to MTHFR A1298C)
300933 Oral Contraceptive/Hormone Replacement Therapy Thrombotic Risk Evaluation (Antithrombin Activity, Factor II Gene Mutation (Prothrombin G20210A), Factor V Leiden, Protein C Activity, Protein S Antigen Free)
300995 Pathology Consultation (Coagulation) - Limited
  PF4 Antibody - see 300522 - Heparin Induced Platelet Antibody, Immunologic
300726 PIVKA-II *RUO*
300126 Plasminogen Activator Inhibitor-1 (PAI-1) Activity
300128 Plasminogen Activator Inhibitor-1 (PAI-1) Antigen
129100 Plasminogen Activator Inhibitor-1, 4G/5G Genotyping *RUO* (PAI-1 polymorphism)
300400 Plasminogen Activity
300408 Plasminogen Antigen
300523 Platelet Antibody, Direct
300521 Platelet Antibody Drug-Induced***
300520 Platelet Antibody Screen, Indirect (HLA, Platelet Glycoprotein)
300936 Platelet Antibody Profile (Platelet antibody screen, platelet antibody direct)
300504 Platelet Factor 4
300805 Platelet Neutralization Procedure
300524 Platelet Specific Antibody (GP IIb/IIIa)
  Platelet Specific Antigen PLA1 (HPA-1a) - see 300531 - HPA-1a (PLA 1 Platelet Antigen Genotyping PLA 2 Polymorphism Detection)
  Platelet Specific Antigen-2 (PLA2) Polymorphism (HPA-1b) - see 300531- HPA-1a (PLA 1 Platelet Antigen Genotyping PLA 2 Polymorphism Detection)
300121 Prekallikrein (Fletcher Factor) Assay
  Prolonged Prothrombin Time or APTT - see 300908 - Abnormal APTT/Prothrombin Time Evaluation
300204 Protein C Activity and Protein S Activity, Protein C Antigen and Protein S Antigen, Total
300149 Protein C Activity and Protein S Activity
300177 Protein C Activity and Protein S Antigen, Free
300142 Protein C Antigen and Protein S Antigen, Total
300035 Protein C Activity (Chromogenic)
300036 Protein C Antigen
300067 Protein C Antigen/Factor VII Antigen Ratio *RUO*
300032 Protein C Antigen, Protein S Antigen/ Factor VII Antigen Ratios *RUO*
300088 Protein S Activity
300087 Protein S Antigen, Free
300038 Protein S Antigen, Total
300929 Protein S Antigen, Total and Free
300059 Protein S Antigen/Factor VII Antigen Ratio *RUO*
300928 Protein S Evaluation (C4b Binding Protein *RUO*, Protein S Activity, Protein S Antigen Free, Protein S Antigen Total)
300340 Protein Z Antigen *RUO*
300718 Prothrombin Fragment 1+ 2, monoclonal
  Prothrombin Gene 20210A Mutation (Factor II Mutation) - see 120736 - Factor II Gene Mutation (Prothrombin G20210A)
  Prothrombin Time Abnormal Evaluation- see 300908 - Abnormal APTT/Prothrombin Time Evaluation
300080 Prothrombin Time/INR
300116 Prothrombin Time Mixing Studies: PT, PT 1:1 NP, PT 1:1 NP 60 min. incubation, PT 1:1 NP 60 min. incubation control
300620 Prothrombinase Induced Clotting Time (Refludan)
300915 Recurrent Miscarriage/Fetal Demise /Obstetric Complications Evaluation (APTT, Anticardiolipin Antibody (IgG, IgM, IgA), Antiphosphatidylserine (IgG, IgM), Antithrombin Activity, Beta-2 Glycoprotein I Antibody (IgG, IgM, IgA), DRVVT, Factor II Gene Mutation (Prothrombin G20210A), Factor V Mutation (Leiden), Hexagonal Phospholipid Neutralization, Homocysteine, Protein C Activity, Protein S Antigen Free.)
300940 Reproductive Health Thrombophilia Profile, Screening APTT, Factor XIII *RUO*, Factor II Gene Mutation (Proghrombin G20210A), Factor V Leiden Mutation, Hexagonal Phospholipid Neutralization, Antithrombin Activity, Protein C Activity (Chromagenic), Protein S Antigen, Free, Anticardiolipin IgG, IgM, IgA, Homocysteine Note: Reflex to immediate APTT mixing studies if APTT is abnormal.
300941 Reproductive Health Thrombophilia Profile, Comprehensive (Activated Partial Thromboplastin Time, Beta-2 GPI, IgG, IgM, IgA, Antiphosphatidylserine, IgG and IgM, Anti-Annexin V, IgG and IgM *RUO*, Anticardiolipin IgG, IgM and IgA, Anti-Prothrombin IgG and IgM, Dilute Russell's Viper Venom Time, Hexagonal Phospholipid Neutralization, Antithrombin Activity- Plasma, Protein C Activity (chromogenic), Protein S Antigen, Free, Factor XIII Activity *RUO*, PAI-1 Activity, Homocysteine, Factor II Gene Mutation (Prothrombin G20210A), Factor V Leiden, MTHFR C677T, Reflex to Immediate APTT mixing studies if APTT is abnormal)
300610 Reptilase Time
  Ristocetin Cofactor - See 300114 - von Willebrand Factor Activity
300082 Serotonin Release Assay (C-14) , Functional Heparin Induced Antibody Assay ***
300611 Stypven Time (RVV) *RUO*
129260 ThrombAssureTM (Factor II Gene Mutation (Prothrombin G20210A) , Factor V Leiden Mutation)
129250 ThrombAssure PlusTM (Factor II Gene Mutation (Prothrombin G20210A), Factor V Leiden Mutation, HR2 Haplotype (A4070G), MTHFR C677T)
300931 ThrombAssure EnhancedTM (Factor II Gene Mutation (Prothrombin G20210A), Factor V Leiden Mutation, Anticardiolipin Antibody (IgG, IgM, IgA), Antithrombin Activity, DRVVT, Hexagonal Phospholipid Neutralization, Homocysteine, Protein C Activity, Protein S Antigen Free)
300932 ThrombAssure InheritedTM (Factor II Gene Mutation (Prothrombin G20210A), Factor V Leiden Mutation, Antithrombin Activity Plasma, Protein C Activity, Protein S Antigen Free)
300714 Thrombin-Antithrombin Complex
300807 Thrombin Time
300813 Thrombin Time Mixing Studies (Thrombin Time, Thrombin Time 1:1 NP Mix, Thrombin Time Heparin Neutralization)
300907 Thrombotic Marker Evaluation (D-Dimer Quantitative, Fibrin Monomer, Prothrombin Fragment 1+2, Thrombin-Antithrombin Complex)
300134 Tissue Plasminogen Activator (TPA) Activity
300125 Tissue Plasminogen Activator (TPA) Antigen
300804 Tissue Thromboplastin Inhibition Test (TTIT)
300914 Venous Occlusion Evaluation (Plasminogen Activator Inhibitor - 1 Activity - Pre-occlusion, Tissue Plasminogen Activator Antigen - Pre-occlusion, Tissue Plasminogen Activator Antigen - Post-occlusion)
300901 Venous Thrombosis (Hypercoagulability) Evaluation (Activated Protein C Resistance, Anticardiolipin Antibody (IgG, IgM), Antithrombin Activity, Factor II Gene Mutation (Prothrombin G20210A), DRVVT, Hexagonal Phospholipid Neutralization, Homocysteine, Protein C Activity (chromogenic), Protein S Antigen Free, Factor VIII Activity) Note: Reflex to Factor V Leiden if APCR is abnormal
300905 Venous Thrombosis Evaluation Appended (Factor IX Activity, Factor XI Activity, Fibrinogen Activity, Fibrinogen Antigen, HR2 Haplotype (A4070G), Lipoprotein (a), Plasminogen Activity)
300903 Venous Thrombosis (Hypercoagulability) Evaluation for Patients on Oral Anticoagulant Therapy (Activated Protein C Resistance, Anticardiolipin Antibody (IgG, IgM), Antithrombin Activity, Factor II Gene Mutation (Prothrombin G20210A), DRVVT, Hexagonal Phospholipid Neutralization, Homocysteine, Protein C Antigen, Protein S Antigen Total, Factor VII Antigen *RUO*, Factor VIII Activity, Protein C Antigen/Factor VII Antigen Ratio *RUO*, Protein S Antigen/Factor VII Antigen Ratio *RUO* Note: Reflex to Factor V Leiden if APCR is abnormal.
300326 von Willebrand Cleaving Protease Profile (ADAMTS13) (von Willebrand Protease Activity and von Willebrand Protease Inhibitor)***
300910 von Willebrand Disease Evaluation (APTT, Collagen Binding Ratio, von Willebrand Factor Collagen Binding Activity, Factor VIII Activity, von Willebrand Factor Activity, von Willebrand Factor Antigen)
300114 von Willebrand Factor Activity (Ristocetin Cofactor)
300113 von Willebrand Factor Antigen (Factor VIII Related Antigen)
300117 von Willebrand Factor Multimers
300318 von Willebrand Factor Protease Inhibitor***
300115 von Willebrand Factor Type 2 N Binding***
300919 von Willebrand Inhibitor Profile (Factor VIII Activity, von Willebrand Factor Antigen, von Willebrand Factor Activity, von Willebrand Activity NP Control, von Willebrand Activity 1:1 NP Mixing Study, von Willebrand Collagen Binding Activity, Collagen Binding ratio, Pathologist interpretation)
  Warfarin Hyper - responsiveness Genotyping - see 300749- CYP2C9 Polymorphism
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